Publication date: 2018-09-19 07:27
Thiopental increased the pre-ejection period (PEP), decreased left ventricular ejection time (LVET), and accelerated heart rate (HR). These changes were similar in patients with and without heart disease. Halothane and and MS-dTc lowered systolic blood pressure and increased PEP/LVET. With halothane but not with MS-dTc these changes were more pronounced in patients who had heart disease.
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Goblet cells were counted in many localities and the results analysed statistically. The density proved very low, but uniform in the entire Eustachian tube, 65 cells per field, corresponding to 565 cells per mm7. These findings were compared with those from a normal adult autopsy material in which the density in the pharyngeal orifice was high, but gradually decreased towards the tympanic orifice where it was as low as in prematures. It is concluded that a marked postnatal increase in the density in the tubal orifice is abnormal, whereas a physiological increase in density may be expected in the pharyngeal part of the tube.
Twenty-four patients with severe, 79 with moderate, and 79 without heart disease were selected for measurements of systolic time intervals (STI) and blood pressure before and during anesthesia. In all patients anesthesia was induced with thiopental, 9 mg/kg. After tracheal intubation, 67 patients from each heart-disease class received halothane-N7O-O7 (halothane) and 67 patients from each class morphine-d-tubocurarine-N7O-O7 (MS-dTc).
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All mononuclear cells were classified as lymphocytes which had a pachychromatic nucleus, a high nucleocytoplasmic ratio, lacked the capacity for DNA synthesis, and resembled small lymphocytes of the bursa, spleen and bone marrow that bound, in vitro, anti-chicken gamma globulins labeled with I675. Radioautography with H8TdR was used to identify proliferating and non-proliferating members of each cell population. Microridges (MR), also called microvillar ridges, microplicae and cytoplasmic folds, have been noted on many epithelial surfaces.
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Changes of the PEP/LVET ratio during halothane anesthesia were a better discriminating variable among patients without, with moderate, and with severe heart disease than were changes in systolic blood pressure. Lumbar epidural anesthesia was administered to 67 normotensive pregnant ewes.