Publication date: 2018-09-18 17:51
The normal adult dose for depression starts with 75 milligrams (mg) a day, taken by mouth, in the morning. It can be increased if symptoms do not improve after a few weeks. The maintenance dose is from 75 to 65 mg a day, and the maximum dose is 85 mg a day.
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect or predict the rates observed in practice.
Immediate-release oral formulations:
Initial dose: 75 mg orally once a day, increased after several weeks if insufficient clinical improvement is observed.
Maintenance dose: 75 to 65 mg orally per day
Maximum dose: 85 mg orally per day
-Doses above 75 mg per day may be given in divided doses, in the morning and at noon
-The full effect may be delayed until after at least 5 weeks of treatment
Use: Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD)
You should not use fluoxetine if you are allergic to it, if you also take pimozide or thioridazine, or if you are being treated with methylene blue injection.
Notes on Rifampicin: Rifampicin may colour urine / tears red and stain contact lenses – do not wear contact lenses for a few days after Rifampicin treatment. If on other drugs, check BNF, product data sheets on / consult pharmacy regarding drug interactions with Rifampicin
If you are using the liquid form of this medication, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Once you re feeling better it s likely that you will continue to take fluoxetine for several more months. Most doctors recommend that you take antidepressants for 6 months to a year after you no longer feel depressed. Stopping before that time can make depression come back.
Seizures: Seizures are a potential risk with antidepressant drugs. Therefore, as with other antidepressants, fluoxetine should be introduced cautiously in patients who have a history of seizures. Treatment should be discontinued in any patient who develops seizures or where there is an increase in seizure frequency. Fluoxetine should be avoided in patients with unstable seizure disorders/epilepsy and patients with controlled epilepsy should be carefully monitored (see section ).
Researchers reported in The American Journal of Psychiatry that for patients with bulimia nervosa who had not responded to psychological treatment, fluoxetine may be a useful intervention. It may provide benefits for bulimia if it is taken for up to a year.